What Is PearlBone™
Information to help you understand what PearlBone™ is, how it is designed to support bone regeneration, and how it may be used as part of your treatment.
What Is PearlBone™?
PearlBone™ is a bone graft material being developed to support the body’s natural bone healing process. It is derived from nacre - a naturally occurring material found in pearl shells - and is engineered with structural characteristics designed to resemble aspects of natural bone architecture.
The material is implanted into a bone defect or trauma site, where it acts as a scaffold to support the cellular processes involved in bone repair. As healing progresses, the material is gradually remodelled and integrated with new bone formation.
PearlBone™ is being developed with a focus on safety, biocompatibility, and controlled medical manufacturing processes. It is currently under research and regulatory review and is not yet available for routine clinical use.
How It Works in the Body
PearlBone™ Putty is specifically designed to be compatible with the human body.
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Nacre is transformed into a biocompatible material designed to support the body’s natural bone repair process.
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PearlBone™ Putty is placed into bony voids or defects in trauma and orthopaedic procedures, where it acts as a scaffold to support early-stage bone repair.
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The targeted particle characteristics of PearlBone™ Putty are designed to support the integration of bone-forming cells during the repair process. Over time, the material is gradually resorbed and replaced as new bone forms within the defect site.
Benefits for Patients
Designed to work with your body
Developed to support the body’s natural bone healing and regeneration processes.
Naturally derived material
Made from a naturally derived material processed to meet medical-grade manufacturing and safety standards.
No permanent implant
Designed to gradually be replaced by the body’s own bone as healing progresses.
Developed with scientific and clinical expertise
Developed through research led by scientists and clinicians with a strong focus on safety, quality, and regulatory standards.
It is currently awaiting regulatory approval in the US followed by Australian human clinical trials commencing in 2026/27.
Patient FAQs
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PearlBone™ is undergoing preclinical testing and regulatory evaluation to assess its safety and performance. Safety, quality, and regulatory compliance are central to its development.
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PearlBone™ is not currently approved by the FDA or TGA for general clinical use. Regulatory evaluation processes are underway, and future availability will depend on regulatory approval.
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PearlBone™ is derived from nacre, a natural material found in pearl shells that has mineral similarities to human bone.
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No. PearlBone™ is designed to gradually be replaced by the body’s own bone as healing progresses.
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PearlBone™ is being developed for use in filling bony voids or gaps caused by injury or surgery, particularly in areas such as the extremities and pelvis.
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Healing and recovery timelines vary between patients and procedures. PearlBone™ is designed to support bone repair within the body’s normal healing process.
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PearlBone™ is still undergoing regulatory review and is not yet approved for clinical use. Please sign up to stay updated on its progress and development.
PearlBone™ has not yet been approved for general clinical use. Future availability will depend on regulatory approvals and completion of the required development and evaluation processes.
The information provided on this website is intended for general informational purposes only and does not replace advice from a qualified healthcare professional.
PearlBone™ is currently undergoing regulatory review
Talk to Your Surgeon
Every patient’s situation is different.
If you are considering treatment options for a bone injury or condition, your treating surgeon or healthcare professional is the best person to advise you. They can explain current treatment approaches and discuss developing technologies such as PearlBone™ within the context of your individual care.